We seek to understand the fundamental principles underlying protein structure and function, to encode these principles in the Rosetta computer program, and to use Rosetta to create a new world of de novo designed proteins to address 21st century challenges in health and technology.
In all cases, we start entirely from first principles; we do not re-engineer native proteins. By iterating between computation and experiment, we continually improve our design methodology.
Our philosophy is that the more closely interacting a research group is, the better the science and the more fun overall. We are always looking for talented, enthusiastic and diverse scientists to join our efforts!
We are located within the Institute for Protein Design at the University of Washington in Seattle.