“The only limit is our imagination.” — David Baker
Read Professor Baker’s full interview to hear his thoughts
on the immense promise of protein design.
We develop protein design software and use it to create molecules that solve challenges in medicine, technology, and sustainability. By iterating between computation and laboratory experiments, we continually improve our protein design methods.
We believe in open collaborative science, and we’re always looking for new people to join our efforts.
Research Areas
Lab Blog
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A WRAP for biology’s greasiest problem
A new way to solubilize membrane proteins without detergents using computationally designed “WRAPs,” making some of biology’s most challenging proteins easier to study.
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Programming proteins with viral geometry
Computationally designed proteins can self-assemble into large, tunable nanocages inspired by viral capsids.
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Mohamad Abedi Receives Michelson Prize: Next Generation Grant
Mohamad is advancing innovative immunology research and therapeutic design.
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Jonas Wilhelm and Chuanyun Xu receive WRF Postdoc Fellowships
Jonas and Chuan are building new climate solutions and tools for neurobiology.
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Building calcium channels from scratch
Even complex biochemical functions that remain only partially understood can now be built from first principles using AI.
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Building protein on/off switches
Medicines that can be rapidly toggled on and off could help end the trade-off between creating powerful drugs and safe ones.