We develop protein design software and use it to create molecules that solve challenges in medicine, technology, and sustainability. By iterating between computation and laboratory experiments, we continually improve our protein design methods.
We believe in open collaborative science, and we’re always looking for new people to join our efforts.
Research Areas
Transitions
| April 2025 | • Congratulations to postdoc Arvind Pillai who will be starting his own lab at the Stowers Institute for Medical Research. • Welcome new postdoc Chuanyun Xu, undergrads Lily Nuss and Sophie Gerdes, and visitors Felix Morey-Burrows and Cesar Ramirez Sarmiento. |
| March 2025 | • Congratulations to grad student Marti Tooley on defending her PhD thesis. • Welcome new grad students Avery Yang and Rafi Brent, rotation students Audrey Hayes, Becca Skotheim, Elliot Delfosse, Jiuhan Shi, Minnie Kim, and Rui Xu, and visitors Giona Cattaneo, Jonathan Funk, and Pengfei Ji. |
Lab Blog
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Congrats Roman!
Postdoc Roman Barth, PhD, has received a Harold M. Weintraub Graduate Student Award. He’s now building new molecular machines.
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Designing antibodies with RFdiffusion
Our fine-tuned AI model generates functional antibodies with atomic precision. It’s also free to use.
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Generating new enzymes with complex active sites
Custom catalysts may help break down plastics and synthesize medicines.
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Neutralizing deadly snake toxins
AI-generated proteins that protect animals in the lab promise safer, more accessible antivenoms.
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Congrats Han!
Postdoc Han Raut Altae-Tran, PhD, has received a Life Sciences Research Foundation fellowship. He’s designing RNA-binding proteins to regulate key biological functions.
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Targeted protein degradation through advanced protein design
“We’ve created a new approach that uses simpler components, achieves greater precision, and can be applied to virtually any target molecule on the surface…