David Baker, PhD
Director, Institute for Protein Design
Investigator, Howard Hughes Medical Institute
Henrietta and Aubrey Davis Endowed Professor of Biochemistry, University of Washington
Adjunct Professor, Genome Sciences, Bioengineering, Chemical Engineering, Computer Science, and Physics, University of Washington
ipdadmin@uw.edu (assistant)
Abbas Idris
Grad Student
Adam Broerman
Grad StudentAdam is working out how to design the dynamics (interaction kinetics and conformational change) of protein assemblies.
Adam Chazin-Gray
Grad StudentAdam is focused on the mechanisms of antibiotic resistance and hopes to make novel antimicrobials
Aditya Krishnakumar
Grad StudentAditya is working on cytokine mimics (IL10 and TNF family specifically) for therapeutics.
Al Nelson, PhD
VisitorAl is a Bernard and Claudine Nist Endowed Fellow and Associate Professor of Chemistry in the UW Department of Chemistry
Alexis Courbet, PhD
PostdocAlexis is working to rationally install dynamic and mechanical behavior into de novo protein nanostructures.
Amijai Saragovi, PhD
PostdocAmijai is developing protein-guanine-based optical matter with the aim of constructing tunable reflective systems.
Amir Motmaen
Grad StudentAmir is redesigning T-cell receptors to recognize peptide-MHC antigens of interest for treatment of infectious diseases and cancer.
Andrew Favor
Grad StudentAndrew is interested in designing nanostructures with novel topologies and symmetries.
Anna Lauko
Grad Student
Arvind Pillai, PhD
PostdocArvind is working on the de novo design of an allosterically-regulated protein-protein interactions.
Avi Swartz
Grad StudentAvi is designing new proteins for artificial photosynthesis.
Basile Wicky, PhD
PostdocBasile is trying to design protein-protein interactions with tunable kinetic and thermodynamic binding profiles.
Benedikt Singer
Visitor
Brian Coventry, PhD
Research ScientistBrian is designing protein-protein interactions.
Brian Koepnick, PhD
Research ScientistBrian works on Foldit, a computer game we use to crowdsource problems in protein modeling and design.
Buwei Huang
Grad StudentBuwei is developing de novo protein binders to manipulate cell signaling and achieve ideal functions (e.g. antagonist, agonist).
Caixuan Liu, PhD
PostdocCaixuan is designing minibinders that contain antibody CDR loops.
Cameron Glasscock, PhD
PostdocCameron is designing protein-DNA interactions.
Chan Johng Kim, PhD
PostdocChan Johng is interested in designing proteins that have unique immunological and physiological properties.
Christian Richardson
Grad StudentChristian is designing synthetic nucleocapsids that can deliver nucleic acid cargo into cells.
Clara McCurdy
Grad StudentClara is using designed proteins to study signaling and direct stem cell differentiation.
Cole A DeForest, PhD
VisitorWeyerhaeuser Endowed Professor of Chemical and Bioengineering at UW.
Cullen Demakis
Grad StudentCullen is interested in enzyme design and two-state design.
David Chmielewski, PhD
Postdoc
David Juergens
Grad StudentDavid is interested in developing deep-learning based solutions for protein sequence and structure generation.
David Kim
Research ScientistDavid is designing minibinders and beta-barrels.
David Lee
Grad StudentDavid is excited about understanding how cells work.
Declan Evans, PhD
Postdoc
DéJenaé See
Grad Student
Derrick Hicks, PhD
PostdocDerrick is developing minibinder-drug conjugates.
Dmitri Zorine
PostdocDmitri’s work is centered around making switchable protein-protein interactions.
Doug Tischer, PhD
PostdocDoug is exploring the use of machine learning to extract protein design rules from high-throughput screens.
Edin Muratspahic, PhD
Postdoc
Erin Yang
Grad StudentErin is working on nanocages, targeted delivery, next-generation vaccines, and STEM outreach.
Fatima Angelica Davila-Hernandez
Grad StudentFatima is working on designing scaffolds and protein interfaces to interact with iron oxide surfaces.
Florence Hardy, PhD
VisitorFlorence is visiting from the UK and is working on the computational design of photoenzymes for thermally forbidden chemistry.
Florian Praetorius, PhD
PostdocFlorian is trying to design reconfigurable and dynamic proteins and protein assemblies.
Gyu Rie Lee, PhD
Research ScientistGyu Rie is designing proteins that bind to small molecules.
Hao Shen, PhD
PostdocHao is designing new protein materials.
Harley Pyles, PhD
Research ScientistHarley is designing and testing protein-inorganic hybrid materials.
Helen Eisenach
Grad Student
Hernan Nunez-Ortega
Lab Manager206-685-7127
Hojun Choi, PhD
PostdocHojun is interested in designing proteins that bind to amyloid proteins and intrinsically disordered proteins.
Hsien Wei Yeh, PhD
PostdocHsien Wei (Andy) is designing molecular switches to dissect complex biological systems, and biosensors to guide rapid diagnostic tests.
Ian Humphreys
Grad StudentIan uses deep learning and coevolution to predict proteome-wide protein interactions and oligomeric structures.
Indrek Kalvet, PhD
PostdocIndrek is designing new (metallo)enzymes based on de novo protein scaffolds.
Inna Goreshnik, PhD
Research Scientist
Isaac Lutz
Grad StudentIsaac is using reinforcement learning to design nanocages and peptide binders.
Isaac Sappington
Grad Student
Ivan Anishchenko, PhD
Acting InstructorIvan is developing new methods for protein structure prediction and design including deep-learning based methods.
Jacob Gershon
Grad StudentJacob is interested in generative modelling to address challenges in protein design.
Jason Qian, PhD
Postdoc
Jason Zhang, PhD
PostdocJason is developing molecular tools for Ras signaling.
Jeremiah Sims
Grad Student
Jilliane Perkins, PhD
PostdocJilliane is using designed protein switches to deliver therapeutics to cancer cells expressing a precise combination of surface antigens.
Jinwei Xu, PhD
PostdocJinwei is exploring ways to integrate engineered biological macromolecules with synthetic nanomaterials.
Joseph Watson, PhD
PostdocJoe is trying to design proteins that undergo defined conformational changes in response to different stimuli.
Joshua Lubner, PhD
PostdocJoshua is designing de novo protein nanoparticles that efficiently escape the endosome.
Jungho Chun
Grad StudentJungho is designing proteins that can modulate immune cells to differentiate into certain cell stages and elicit desired immune responses.
Justas Dauparas, PhD
PostdocJustas is developing machine learning methods for protein structure prediction and design.
Kandise Van Wormer
Sr. Lab Manager206-685-7127
Kejia Wu
Grad StudentKejia is developing methods for binding linear peptides and intrinsically disordered proteins, and exploring their functions in nature.
Kenneth Carr
Lab Manager206-685-7127
Kiera Sumida
Grad StudentKiera is leveraging Rosetta and deep-learning methods to discover and design novel PET hydrolases.
Kirsten Thompson
Grad StudentKirsten is broadly interested immunomodulation and cancer immunotherapy applications of protein design.
Linna An, PhD
PostdocLinna designs protein binders for small molecules and peptide binders for protein complexes.
Lisa Brandenburg
VisitorLisa is Dutch Master’s student from Utrecht University interested in biochemistry and all things peptide/protein-related.
Ljubica Mihaljevic, PhD
PostdocLjubica is designing transmembrane proteins that function as biosensors.
Long Tran
Grad Student
Lucas Arnoldt
Visitor
Lukas Milles, PhD
PostdocLukas is designing robust protein folds as well as intra- and intermolecular isopeptide bonds.
Magnus Bauer, PhD
PostdocMagnus is exploring the design of kinases and protein-based inhibitors to decode and manipulate cellular logic.
Marc Exposit
Grad StudentMarc is interested in protein design approaches that combine scaffold generation with the binding of a target of interest.
Marti Rae Tooley
Grad Student
Matthias Gloegl, PhD
PostdocMatthias is designing novel antiviral inhibitors, immunomodulators, and vaccines.
Mohamad Abedi, PhD
PostdocMohamad is interested in designing proteins to engineer and control cellular function.
Nate Bennett
Grad StudentNate is developing computational methods to improve the design of polar protein-protein interfaces.
Nate Ennist, PhD
PostdocNate is designing proteins for artificial photosynthesis with the long-term goal of producing renewable fuel.
Neville Bethel, PhD
PostdocNeville is interested in the mechanical properties of protein assemblies.
Nicole Roullier
Research Scientist
Nikita Hanikel, PhD
Postdoc
Pascal Sturmfels
Grad StudentPascal is developing deep learning methods for structure prediction and small molecule docking.
Patrick Erickson, PhD
PostdocPat is interested in designing miniprotein therapeutics with non-canonical amino acids.
Paul Kim
Grad StudentPaul is developing machine learning methods for protein design.
Peik Lund-Andersen
Grad Student
Phil Leung
PostdocPhil is trying to make proteins that have two defined structural states.
Preetham Venkatesh
Grad StudentPreetham is designing protein-based therapeutics for chronic pain and metabolic disorders
Rob Ragotte, PhD
PostdocRob designs protein binders for applications in infectious disease.
Robert Pecoraro
Grad StudentRobert is working on the computational design of proteins that bind specific DNA sequences.
Roberta Lucchi
Visitor
Rohith Krishna
Grad StudentRohith is developing deep learning methods for structure prediction and design.
Ryan Kibler
PostdocRyan is developing a generalized method for transforming homo-oligomers into pseudosymmetric hetero-oligomers.
Ryan McHugh
Grad StudentRyan is working on structure prediction and the design of protein-nucleic acid complexes.
Sagardip Majumder, PhD
PostdocSagardip is designing new transmembrane transport proteins.
Sam Pellock, PhD
PostdocSam is interested in developing new experimental approaches to rapidly measure functions.
Samuel Berhanu, PhD
PostdocSamuel is working on the de novo design of membrane proteins.
Samuel Thompson, PhD
Postdoc
Sangmin Lee, PhD
PostdocSangmin is interested in designing protein nanocages and complex nanostructures.
Sanjay Srivatsan, PhD
PostdocSanjay is trying to deploy sequencing-based technologies to screen binders.
Shingo Honda, PhD
PostdocShingo is trying to assemble asymmetric protein oligomers based on cooperative interactions between each monomer.
Shruti Jain
Grad Student
Shunzhi Wang, PhD
PostdocShunzhi is interested in designing self-assembling protein nanomaterials, including capsids, 2D lattices, and 3D crystals.
Sidney Lisanza
Grad StudentSidney is designing proteins to modulate the immune system in a predefined manner.
Stephanie Hanna
Grad StudentStephanie is designing de novo, chemically inducible dimerization systems.
Susana Vazques Torres
Grad StudentSusana is designing proteins that interact with small molecules and other proteins.
Ta-Yi Yu, PhD
Postdoc Teresa Schaaf
Research Scientist
Thomas Schlichthärle, PhD
PostdocThomas is working to create superagonists from miniprotein binders that spatiotemporally control cell signaling.
Tim Huddy, PhD
Research ScientistTim works on designing proteins that are like LEGO® building blocks.
Wei (Will) Chen, PhD
PostdocWill is interested in building new technology that can help us understand nature.
Wei Yang, PhD
PostdocWei is interested in designing protein minibinders.
Will Sheffler, PhD
Research ScientistWill develops useful code.
William White
Grad StudentWill is using designed protein scaffolds to present antigens and co-stimulation to T-cells.
Woody Ahern
Grad Student
Xinru Wang, PhD
PostdocXinru wants to design binders that target native proteins to regulate their functions.
Yakov Kipnis, PhD
Research ScientistYakov is working on computational enzyme design.
Yang Hsia, PhD
Research ScientistYang develops methods for designing new protein-based materials.
Yujia Wang, PhD
PostdocYujia is designing de novo protein binders for protein-protein interfaces and small molecules for therapeutic applications.
Yulai Liu
Grad StudentYulai is designing membrane proteins that can function as biosensors.
Zhe Li, PhD
PostdocZhe is studying annealing in protein self-assembly and designing 3D protein crystals.
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