David Baker, PhD
Director, Institute for Protein Design
Investigator, Howard Hughes Medical Institute
Henrietta and Aubrey Davis Endowed Professor of Biochemistry, University of Washington School of Medicine
Adjunct Professor, Genome Sciences, Bioengineering, Chemical Engineering, Computer Science, and Physics, University of Washington
Mohamad Abedi
Postdoc
mabedi
Mohamad is designing proteins to understand and manipulate cell signaling networks
Woody Ahern
Grad Student
ahern
Green Ahn
Postdoc
greenahn
Green is designing proteins to modulate cellular processes involved in cancer.
Ali Alattar
Undergrad
aalattar
Ali is designing phosphorylation-inducible heterodimers.
Han Raut Altae-Tran
Postdoc
altaeth
Han is studying nucleic acids and design methods
Linna An
Postdoc
linnaan
Linna An developed ML-based small molecule binding and sensing pipelines.
Pooja Bandawane
Grad Student
banda14
Roman Barth
Postdoc
robarth
Roman is designing novel enzymatic molecular motors.
Magnus Bauer
Postdoc
magnusb
Magnus is exploring the design of kinases and protein-based inhibitors to decode and manipulate cellular logic.
Riti Biswas
Grad Student
ritib
Riti is working on antibody design to accelerate biologic therapeutics R&D.
Yang Bo
Postdoc
yangbo
Yang is designing proteins for tissue-specific drug delivery.
Julia Bonzanini
Grad Student
jbonz
Julia is making proteins that can specifically bind to peptide-MHC molecules for cancer immunotherapy.
Adam Broerman
Grad Student
broerman
Adam is designing motions, mechanics, and kinetics of dynamic protein assemblies.
Adam Chazin-Gray
Grad Student
achazing
Wei Chen
Postdoc
wchen108
Wei is designing proteins to modulate gene expression
Yvonne Chen
Visitor
chenyv
Anqi Chen
Postdoc
achen918
Anqi is interested in generating very specific proteases.
David Chmielewski
Postdoc
djchmiel
David is interested in designing complex protein nanoparticles for diverse applications.
Hojun Choi
Postdoc
lepionce
Hojun is interested in designing protein tools to control and sense endogenous signaling events.
Hojae Choi
Grad Student
hojaec
Rishabh Chowhan
Staff
rchowhan
Rishabh is designing de novo protein binders to modulate cell signaling for various medical applications.
Jennifer Chun
Undergrad
mchun1
Jung Ho Chun
Postdoc
jhchun
Jungho is designing proteins that modulate immune cells to differentiate into specific cell stages and elicit desired immune responses.
Nate Corley
Grad Student
ncorley
Nate is developing deep-learning methods for enzyme design and activity prediction
Alexis Courbet
Acting Instructor
acourbet
Alexis is a protein nanomachine designer and AI-based protein design researcher, exploring the field from first principles to translation.
Brian Coventry
Staff
bcov
Brian is trying to understand the forces that stick proteins together
Cullen Demakis
Grad Student
cdemakis
Cullen is designing protein motors that cycle between multiple well-defined states under power.
Kristin Ding
Undergrad
haozhd2
Rose Duong
Undergrad
rduong1
Rose is designing proteins which undergo light-induced conformational change.
Helen Eisenach
Grad Student
heisen
Nathan Ennist
Acting Instructor
ennist
Nate is designing proteins for artificial photosynthesis with the long-term goal of producing renewable fuel.
Declan Evans
Postdoc
dme5188
Declan is designing enzymes for reactions not observed in Nature
Marc Exposit
Grad Student
mexposit
Samir Faruq
Undergrad
sfaruq
Andrew Favor
Grad Student
afavor
Andrew is developing deep learning models to design complexes containing both proteins and nucleic acids.
Timo Fluegel
Postdoc
fluegelt
Mariana Garcia Sanchez
Staff
marigs
Jacob Gershon
Grad Student
jgershon
Cameron Glasscock
Acting Instructor
cjg263
Cameron is working on methods for design of DNA binding proteins.
Matthias Gloegl
Postdoc
mgloegl
Matthias is designing de novo antagonists and agonists for treatment of autoinflammatory disease and cancer.
Inna Goreshnik
Staff
ig1983
Nathan Greenwood
Staff
forest77
Nathan is designing protein binders to target cancer and increase our understanding of biology.
William Grubbe
Postdoc
wgrubbe
Will is designing smart protein therapeutics.
Laura Guerrero
Grad Student
lgue26
Laura is designing peptide-MHC scaffolds to enable the understanding of peptide-specific disease associations.
Zhichun Guo
Postdoc
zcguo
Zhichun is developing deep learning methods to enhance the prediction of protein binding interactions
Ella Haefner
Grad Student
ellahaef
Nikita Hanikel
Postdoc
nhanikel
Nikita is working on the design of de novo metalloproteins
Stephanie Hanna
Grad Student
hannas1
Florence Hardy
Postdoc
fjhardy
Florence is designing light activated enzymes using noncanonical amino acid photosensitisers.
Luca Herrmann
Visitor
herrluca
Derrick Hicks
Staff
drhicks1
Shingo Honda
Postdoc
shhonda
Shingo is designing asymmetric protein assembly aided by a peptide scaffold.
Yang Hsia
Staff
yhsia
Yang is interested in designing protein and protein-adjacent bio-materials across different length scales (nano- to macro-scale).
Tim Huddy
Staff
thuddy
Andrew Hunt
Postdoc
ach94
Andrew designs enzymes and develops methods for collecting and using large amounts of data to improve design outcomes.
Abbas Idris
Grad Student
aidris1
Marouane Jaakik
Visitor
mj84
Shruti Jain
Grad Student
sjain2
Joy Jang
Undergrad
yewonj
Jihun Jeung
Grad Student
jeung
Indrek Kalvet
Staff
ikalvet
Indrek is designing new enzymes based on catalytic cofactor binding.
Sebastian Kenny
Postdoc
skenny97
Kenny is designing minibinder proteins to perform targeted protein degradation for novel therapeutic applications.
Ryan Kibler
Postdoc
rdkibler
Ryan is designing proteins for purifying non-biological compounds of industrial interest
Chan Johng Kim
Postdoc
chanjkim
Chan is designing cytokine mimics to boost anti-cancer immunity with fewer side effects, activating only in tumor-specific environments
Paul Kim
Grad Student
ptkim
Paul is working on generative models for design of DNA-binding-proteins, with the eventual goal of optimizing for specificity.
David Kim
Staff
dekim
Donghyo Kim
Postdoc
donghyo
Donghyo is designing de novo enzymes using deep learning methods.
Yakov Kipnis
Staff
yak
Yakov is working on computational enzyme design.
Owen Henry Knight
Undergrad
ohknight
Rohith Krishna
Grad Student
rohith
Rohith is developing neural networks for structure prediction and design.
Aditya Krishnakumar
Grad Student
aditya20
Andrew Kubaney
Grad Student
akubaney
Paul Kwon
Grad Student
pkwon2
Paul is working on biomineralization and DNA binding.
Anna Lauko
Grad Student
laukoa
Anna is designing new enzymes.
Seulhoo Lee
Postdoc
seulh
Gyu Rie Lee
Staff
gyurie
Gyu Rie is designing binders and modulators in all-atom resolution by developing ML-based methods.
David Lee
Grad Student
davidsl
Mauriz Lichtenstein
Visitor
mlicht
Mauriz is a visiting Masters student from the FU Berlin and working on redesigning TCRs and cytokines to target cancers.
Michelin Lin
Staff
hl0320
Michelin is using transmembrane beta-barrel proteins as nanopores to advance DNA and protein sequencing technologies.
Caixuan Liu
Postdoc
lcx425
Caixuan is doing protein design of IDP
Yulai Liu
Grad Student
ylliu15
Bingxu Liu
Postdoc
bxliu
Bingxu is working on transforming living system evolution logic from try-and-error to rational design.
Beau Lonnquist
Undergrad
blonn25
Beau is designing de novo transcription factors to regulate gene expression.
Peik Lund-Andersen
Grad Student
peikl
Peik is designing redox enzymes and electron transport proteins for artificial photosynthesis
Meg Lunn-Halbert
Grad Student
mlunn1
Meg is a BPSD graduate student in the King and Baker labs. She is working to improve vaccine efficacy using de novo protein design.
David Mai
Postdoc
damai
Sagardip Majumder
Postdoc
sagardip
Sagardip is interested in engineering membrane proteins akin to natural ones and using protein design for nanopore applications.
Clara McCurdy
Grad Student
cmccurdy
Clara is designing proteins to edit the epigenome and stabilize blood vessels for therapeutics.
Ryan McHugh
Grad Student
rpmchugh
Ryan is training machine learning models specialized for predicting the structure and specificity of DNA-binding proteins.
Nora McNamara-Bordewick
Grad Student
noramcb
Ljubica Mihaljevic
Postdoc
ljubim
Ljubica is solubilizing native membrane proteins using de novo protein design and is also making transmembrane proteins for scratch
Joe Min
Grad Student
joemin
Joe is interested in developing methods to redesign native enzymes to combat the effects of climate change.
Uma Mitchell
Undergrad
umam3
Oliver Morell
Visitor
omorell
Oliver is exploring how protein design models can generate cross-reactive and/or specific binders by considering multiple targets
Amir Motmaen
Grad Student
amotmaen
Amir is working on using protein design to program and direct T cell for immunotherapy applications targeting solid tumors.
Edin Muratspahic
Postdoc
edinm2
Edin is working on de novo design of binders targeting G protein-coupled receptors (GPCRs)
Molly Park
Undergrad
parkmoll
Hazel Patro
Undergrad
hpatro
Robert Pecoraro
Grad Student
robpec
Robert is working on the computational design of proteins that bind specific DNA sequences.
Sam Pellock
Acting Instructor
spellock
Sam is interested in designing enzymes that go fast.
Annika Philomin
Grad Student
aphilo
Annika is designing transmembrane beta barrel proteins for small molecule sensing by improving deep learning methods
Arvind Pillai
Postdoc
apillai1
Arvind is working on the design of allosterically switchable enzymes, with the aim of building useful protein sensors and nanomachines.
Yuliya Politanska
Grad Student
ypolit
Harley Pyles
Staff
pylesh
Harley is designing and characterizing proteins to control the formation of minerals
Jason Qian
Postdoc
jq01
enzyme design
Nathen Qing
Undergrad
yinathen
Xiangli Qu
Postdoc
xiangliq
Xiangli is interested in designing protein binders to modulate the function of membrane proteins like GPCRs
Riley Quijano
Grad Student
rnquijan
Riley is using both DNA-binder design and enzyme design to make de novo nucleases capable of cutting new recognition sites.
Robert Ragotte
Postdoc
ragotte
Rob is designing proteins that neutralize pathogens and alter cell signalling pathways
Nicole Roullier
Staff
roullnl
Shayan Sadre
Grad Student
ssadre
Shayan is interested in designing binders to modulate protein homeostasis.
Saman Salike
Grad Student
ssalike
Stephanie Sansbury
Postdoc
ssans
Steph is engineering nanoparticle-compatible designs to facilitate efficient delivery of intracellularly-targeted therapeutic cargos
Isaac Sappington
Grad Student
ikesapp
Isaac is developing methods to solve protein-protein interface design, enabling the creation of de novo protein therapeutics and cytokines
Amijai Saragovi
Postdoc
amijais
Most of the basic principles underlying protein derived biomineralization remain poorly understood. Using a large set of engineered protein
Christina Savvides
Grad Student
savvides
Christina is interested in designing immunomodulators to treat autoimmune diseases.
Thomas Schlichthaerle
Postdoc
thomschl
Thomas is interested in designing super agonists to modulate cellular decision making.
DeJenae See
Grad Student
dlsee
Enisha Sehgal
Grad Student
esehgal
Enisha is designing DNA binding proteins to modulate gene expression and edit genomes.
Shajesh Sharma
Grad Student
shajesh
Shajesh is using protein design to optimize engineered metabolic pathways.
Will Sheffler
Staff
wsheffle
Kathryn Shelley
Postdoc
ks427
Kathryn is designing proteins that undergo light-driven conformational change.
Hao Shen
Postdoc
shenh2
Hao is designing self-assembling protein filament nanomaterials
Alexander Shida
Grad Student
ashida
Hojeong Shin
Postdoc
hojshin
Hojeong is designing proteins to modulate immune cells in a tumor-specific manner
Ellen Shrock
Postdoc
eshrock
Ellen is studying determinants of immunogenicity.
Jeremiah Sims
Postdoc
simsjn
Jeremiah is an MSTP student at the UW, where he uses computational tools to make potent, broadly-neutralizing antivirals.
Abhishek Singh
Postdoc
as393
Abhishek is exploring how to create highly asymmetric protein assemblies with precise control over shape and size.
Zihao Song
Grad Student
zhsong
Zihao is interested in designing a synthetic proteome and an artificial cell
Ria Sonigra
Grad Student
rias04
Ria is working on de novo design of nanopores for biosensing applications
Kiera Sumida
Grad Student
khsumida
Kiera is designing enzymes for plastic degradation.
Eric Sun
Grad Student
suneric
Avi Swartz
Grad Student
azswartz
Avi is designing new photosystems for artificial photosynthesis
Mia Switzer
Undergrad
miaswit
Kirsten Thompson
Grad Student
kathomps
Kirsten is working on de novo protein and cellular cancer immunotherapies.
Tuscan Rock Thompson
Grad Student
tuscant
Marti Rae Tooley
Grad Student
bellm7
Marti is interested in modulating the immune response to vaccines through protein designed nanoparticles to generate long lasting response.
Long Tran
Grad Student
lhtran
Long is interested in developing methods for designing small molecule binding proteins
Dionne Vafeados
Staff
vafeados
Preetham Venkatesh
Grad Student
preetham
Preetham is designing sequence-specific proteases
Shunzhi Wang
Acting Instructor
swang523
Xinru Wang
Acting Instructor
xinruw7
Yujia Wang
Postdoc
yujiaw21
Yujia is interested in designing enzymes to address challenges in biotechnology and organic synthesis.
James Watson
Visitor
jamesw53
Roni Weissman
Grad Student
ronimw
Roni is working on designing new nanocage modalities for delivery.
Jonas Wilhelm
Postdoc
jonaswil
Jonas is designing enzymes that catalyze new-to-nature reactions
Max Witwer
Undergrad
mwitwer
Seth Woodbury
Grad Student
woodbuse
Seth is designing de novo (metallo)enzymes from transition state theozymes for diverse catalytic and photocatalytic applications.
Kejia Wu
Grad Student
kejiawu
Kejia is on method development for binding peptides/intrinsically disordered regions, and functionalizing the binders.
Jinwei Xu
Postdoc
jinweixu
Fanglei Xue
Visitor
faxue
Fanglei is developing machine intelligence models to improve the success rate of protein design.
Tracy Yu
Postdoc
tracyy2
Tracy is working on developing bone-mimetic materials via hydroxyapatite mineralization proteins.
Jason Zhang
Postdoc
jzz0428
Jason Zhang is designing molecular tools to understand and manipulate cancer cell signaling.
Olivia Zhu
Undergrad
siyuzhu