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31 entries « 1 of 2 »
1.

Craven, Timothy W.; Nolan, Mark D.; Bailey, Jonathan; Olatunji, Samir; Bann, Samantha J.; Bowen, Katherine; Ostrovitsa, Nikita; Costa, Thaina M. Da; Ballantine, Ross D.; Weichert, Dietmar; Levine, Paul M.; Stewart, Lance J.; Bhardwaj, Gaurav; Geoghegan, Joan A.; Cochrane, Stephen A.; Scanlan, Eoin M.; Caffrey, Martin; Baker, David

Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase Journal Article

In: ACS Chemical Biology, 2024.

Abstract | Links | BibTeX

2.

Hicks DR An L, Zorine D

Hallucination of closed repeat proteins containing central pockets Journal Article

In: Nature Structural & Molecular Biology, 2023.

Abstract | Links | BibTeX

3.

Goldbach, Nicolas; Benna, Issa; Wicky, Basile I. M.; Croft, Jacob T.; Carter, Lauren; Bera, Asim K.; Nguyen, Hannah; Kang, Alex; Sankaran, Banumathi; Yang, Erin C.; Lee, Kelly K.; Baker, David

De novo design of monomeric helical bundles for pH-controlled membrane lysis Journal Article

In: Protein Science, 2023.

Abstract | Links | BibTeX

4.

Wang, Jing Yang (John); Khmelinskaia, Alena; Sheffler, William; Miranda, Marcos C.; Antanasijevic, Aleksandar; Borst, Andrew J.; Torres, Susana V.; Shu, Chelsea; Hsia, Yang; Nattermann, Una; Ellis, Daniel; Walkey, Carl; Ahlrichs, Maggie; Chan, Sidney; Kang, Alex; Nguyen, Hannah; Sydeman, Claire; Sankaran, Banumathi; Wu, Mengyu; Bera, Asim K.; Carter, Lauren; Fiala, Brooke; Murphy, Michael; Baker, David; Ward, Andrew B.; King, Neil P.

Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains Journal Article

In: Proceedings of the National Academy of Sciences, 2023.

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5.

Bhardwaj, Gaurav; O’Connor, Jacob; Rettie, Stephen; Huang, Yen-Hua; Ramelot, Theresa A.; Mulligan, Vikram Khipple; Alpkilic, Gizem Gokce; Palmer, Jonathan; Bera, Asim K.; Bick, Matthew J.; Piazza, Maddalena Di; Li, Xinting; Hosseinzadeh, Parisa; Craven, Timothy W.; Tejero, Roberto; Lauko, Anna; Choi, Ryan; Glynn, Calina; Dong, Linlin; Griffin, Robert; van Voorhis, Wesley C.; Rodriguez, Jose; Stewart, Lance; Montelione, Gaetano T.; Craik, David; Baker, David

Accurate de novo design of membrane-traversing macrocycles Journal Article

In: Cell, 2022.

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6.

Macé, Kévin; Vadakkepat, Abhinav K.; Redzej, Adam; Lukoyanova, Natalya; Oomen, Clasien; Braun, Nathalie; Ukleja, Marta; Lu, Fang; Costa, Tiago R. D.; Orlova, Elena V.; Baker, David; Cong, Qian; Waksman, Gabriel

Cryo-EM structure of a type IV secretion system Journal Article

In: Nature, 2022.

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7.

Vorobieva, Anastassia A.; White, Paul; Liang, Binyong; Horne, Jim E.; Bera, Asim K.; Chow, Cameron M.; Gerben, Stacey; Marx, Sinduja; Kang, Alex; Stiving, Alyssa Q.; Harvey, Sophie R.; Marx, Dagan C.; Khan, G. Nasir; Fleming, Karen G.; Wysocki, Vicki H.; Brockwell, David J.; Tamm, Lukas K.; Radford, Sheena E.; Baker, David

De novo design of transmembrane beta barrels Journal Article

In: Science, vol. 371, no. 6531, 2021.

Abstract | Links | BibTeX

8.

Ben-Sasson, Ariel J.; Watson, Joseph L.; Sheffler, William; Johnson, Matthew Camp; Bittleston, Alice; Somasundaram, Logeshwaran; Decarreau, Justin; Jiao, Fang; Chen, Jiajun; Mela, Ioanna; Drabek, Andrew A.; Jarrett, Sanchez M.; Blacklow, Stephen C.; Kaminski, Clemens F.; Hura, Greg L.; De Yoreo, James J.; Kollman, Justin M.; Ruohola-Baker, Hannele; Derivery, Emmanuel; Baker, David

Design of biologically active binary protein 2D materials Journal Article

In: Nature, 2021.

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9.

Xu, Chunfu; Lu, Peilong; El-Din, Tamer M. Gamal; Pei, Xue Y.; Johnson, Matthew C.; Uyeda, Atsuko; Bick, Matthew J.; Xu, Qi; Jiang, Daohua; Bai, Hua; Reggiano, Gabriella; Hsia, Yang; Brunette, T J; Dou, Jiayi; Ma, Dan; Lynch, Eric M.; Boyken, Scott E.; Huang, Po-Ssu; Stewart, Lance; DiMaio, Frank; Kollman, Justin M.; Luisi, Ben F.; Matsuura, Tomoaki; Catterall, William A.; Baker, David

Computational design of transmembrane pores Journal Article

In: Nature, vol. 585, pp. 129–134, 2020.

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10.

Boyken, Scott E.; Benhaim, Mark A.; Busch, Florian; Jia, Mengxuan; Bick, Matthew J.; Choi, Heejun; Klima, Jason C.; Chen, Zibo; Walkey, Carl; Mileant, Alexander; Sahasrabuddhe, Aniruddha; Wei, Kathy Y.; Hodge, Edgar A.; Byron, Sarah; Quijano-Rubio, Alfredo; Sankaran, Banumathi; King, Neil P.; Lippincott-Schwartz, Jennifer; Wysocki, Vicki H.; Lee, Kelly K.; Baker, David

De novo design of tunable, pH-driven conformational changes Journal Article

In: Science, vol. 364, no. 6441, pp. 658-664, 2019.

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11.

Lu, Peilong; Min, Duyoung; DiMaio, Frank; Wei, Kathy Y.; Vahey, Michael D.; Boyken, Scott E.; Chen, Zibo; Fallas, Jorge A.; Ueda, George; Sheffler, William; Mulligan, Vikram Khipple; Xu, Wenqing; Bowie, James U.; Baker, David

Accurate computational design of multipass transmembrane proteins Journal Article

In: Science, vol. 359, no. 6379, pp. 1042–1046, 2018, ISSN: 0036-8075.

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12.

Ovchinnikov, Sergey; Park, Hahnbeom; Varghese, Neha; Huang, Po-Ssu; Pavlopoulos, Georgios A.; Kim, David E.; Kamisetty, Hetunandan; Kyrpides, Nikos C.; Baker, David

Protein structure determination using metagenome sequence data Journal Article

In: Science, vol. 355, no. 6322, pp. 294–298, 2017, ISSN: 0036-8075.

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13.

Holstein, Carly A; Chevalier, Aaron; Bennett, Steven; Anderson, Caitlin E; Keniston, Karen; Olsen, Cathryn; Li, Bing; Bales, Brian; Moore, David R; Fu, Elain; Baker, David; Yager, Paul

Immobilizing affinity proteins to nitrocellulose: a toolbox for paper-based assay developers. Journal Article

In: Analytical and bioanalytical chemistry, 2015, ISSN: 1618-2650.

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14.

Bergeron, Julien R C; Worrall, Liam J; De, Soumya; Sgourakis, Nikolaos G; Cheung, Adrienne H; Lameignere, Emilie; Okon, Mark; Wasney, Gregory A; Baker, David; McIntosh, Lawrence P; Strynadka, Natalie C J

The modular structure of the inner-membrane ring component PrgK facilitates assembly of the type III secretion system basal body Journal Article

In: Structure (London, England : 1993), vol. 23, pp. 161-72, 2015, ISSN: 1878-4186.

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15.

Chen, Kuang-Yui M; Sun, Jiaming; Salvo, Jason S; Baker, David; Barth, Patrick

High-resolution modeling of transmembrane helical protein structures from distant homologues. Journal Article

In: PLoS computational biology, vol. 10, pp. e1003636, 2014, ISSN: 1553-7358.

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16.

Geibel, Sebastian; Procko, Erik; Hultgren, Scott J; Baker, David; Waksman, Gabriel

Structural and energetic basis of folded-protein transport by the FimD usher Journal Article

In: Nature, vol. 496, pp. 243-6, 2013, ISSN: 1476-4687.

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17.

Bergeron, Julien R C; Worrall, Liam J; Sgourakis, Nikolaos G; DiMaio, Frank; Pfuetzner, Richard A; Felise, Heather B; Vuckovic, Marija; Yu, Angel C; Miller, Samuel I; Baker, David; Strynadka, Natalie C J

A Refined Model of the Prototypical Salmonella SPI-1 T3SS Basal Body Reveals the Molecular Basis for Its Assembly Journal Article

In: PLoS pathogens, vol. 9, pp. e1003307, 2013, ISSN: 1553-7374.

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18.

Demers, Jean-Philippe; Sgourakis, Nikolaos G; Gupta, Rashmi; Loquet, Antoine; Giller, Karin; Riedel, Dietmar; Laube, Britta; Kolbe, Michael; Baker, David; Becker, Stefan; Lange, Adam

The common structural architecture of Shigella flexneri and Salmonella typhimurium type three secretion needles Journal Article

In: PLoS pathogens, vol. 9, pp. e1003245, 2013, ISSN: 1553-7374.

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19.

Yarov-Yarovoy, Vladimir; DeCaen, Paul G; Westenbroek, Ruth E; Pan, Chien-Yuan; Scheuer, Todd; Baker, David; Catterall, William A

Structural basis for gating charge movement in the voltage sensor of a sodium channel Journal Article

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 109, pp. E93-102, 2012, ISSN: 1091-6490.

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20.

Saha, Piyali; Barua, Bipasha; Bhattacharyya, Sanchari; Balamurali, M M; Schief, William R; Baker, David; Varadarajan, Raghavan

Design and characterization of stabilized derivatives of human CD4D12 and CD4D1 Journal Article

In: Biochemistry, vol. 50, pp. 7891-900, 2011, ISSN: 1520-4995.

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31 entries « 1 of 2 »