Publications

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78 entries « 4 of 4 »
61.

Baker, David

An exciting but challenging road ahead for computational enzyme design Journal Article

In: Protein science, 2010, ISSN: 1469-896X.

BibTeX

62.

Siegel, Justin B; Zanghellini, Alexandre; Lovick, Helena M; Kiss, Gert; Lambert, Abigail R; Clair, Jennifer L St; Gallaher, Jasmine L; Hilvert, Donald; Gelb, Michael H; Stoddard, Barry L; Houk, Kendall N; Michael, Forrest E; Baker, David

Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction Journal Article

In: Science, vol. 329, pp. 309-13, 2010, ISSN: 1095-9203.

Abstract | BibTeX

63.

Khersonsky, Olga; R"othlisberger, Daniela; Dym, Orly; Albeck, Shira; Jackson, Colin J; Baker, David; Tawfik, Dan S

Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series Journal Article

In: Journal of Molecular Biology, vol. 396, pp. 1025-42, 2010, ISSN: 1089-8638.

Abstract | Links | BibTeX

64.

Thyme, Summer B; Jarjour, Jordan; Takeuchi, Ryo; Havranek, James J; Ashworth, Justin; Scharenberg, Andrew M; Stoddard, Barry L; Baker, David

Exploitation of binding energy for catalysis and design Journal Article

In: Nature, vol. 461, pp. 1300-4, 2009, ISSN: 1476-4687.

Abstract | BibTeX

65.

Murphy, Paul M; Bolduc, Jill M; Gallaher, Jasmine L; Stoddard, Barry L; Baker, David

Alteration of enzyme specificity by computational loop remodeling and design Journal Article

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 106, pp. 9215-20, 2009, ISSN: 1091-6490.

Abstract | BibTeX

66.

Dietrich, Jeffrey A; Yoshikuni, Yasuo; Fisher, Karl J; Woolard, Frank X; Ockey, Denise; McPhee, Derek J; Renninger, Neil S; Chang, Michelle C Y; Baker, David; Keasling, Jay D

A novel semi-biosynthetic route for artemisinin production using engineered substrate-promiscuous P450(BM3) Journal Article

In: ACS chemical biology, vol. 4, pp. 261-7, 2009, ISSN: 1554-8937.

Abstract | BibTeX

67.

Muratore, Kathryn E; Seeliger, Markus A; Wang, Zhihong; Fomina, Dina; Neiswinger, Johnathan; Havranek, James J; Baker, David; Kuriyan, John; Cole, Philip A

Comparative analysis of mutant tyrosine kinase chemical rescue Journal Article

In: Biochemistry, vol. 48, pp. 3378-86, 2009, ISSN: 1520-4995.

Abstract | BibTeX

68.

Alexandrova, Anastassia N; R"othlisberger, Daniela; Baker, David; Jorgensen, William L

Catalytic mechanism and performance of computationally designed enzymes for Kemp elimination Journal Article

In: Journal of the American Chemical Society, vol. 130, pp. 15907-15, 2008, ISSN: 1520-5126.

Abstract | BibTeX

69.

Cho, Hyundae D; Sood, Vanita D; Baker, David; Weiner, Alan M

On the role of a conserved, potentially helix-breaking residue in the tRNA-binding alpha-helix of archaeal CCA-adding enzymes Journal Article

In: RNA, vol. 14, pp. 1284-9, 2008, ISSN: 1469-9001.

Abstract | BibTeX

70.

R"othlisberger, Daniela; Khersonsky, Olga; Wollacott, Andrew M; Jiang, Lin; DeChancie, Jason; Betker, Jamie; Gallaher, Jasmine L; Althoff, Eric A; Zanghellini, Alexandre; Dym, Orly; Albeck, Shira; Houk, Kendall N; Tawfik, Dan S; Baker, David

Kemp elimination catalysts by computational enzyme design Journal Article

In: Nature, vol. 453, pp. 190-5, 2008, ISSN: 1476-4687.

Abstract | BibTeX

71.

Jiang, Lin; Althoff, Eric A; Clemente, Fernando R; Doyle, Lindsey; R"othlisberger, Daniela; Zanghellini, Alexandre; Gallaher, Jasmine L; Betker, Jamie L; Tanaka, Fujie; Barbas, Carlos F; Hilvert, Donald; Houk, Kendall N; Stoddard, Barry L; Baker, David

De novo computational design of retro-aldol enzymes Journal Article

In: Science, vol. 319, pp. 1387-91, 2008, ISSN: 1095-9203.

Abstract | BibTeX

72.

Zanghellini, Alexandre; Jiang, Lin; Wollacott, Andrew M; Cheng, Gong; Meiler, Jens; Althoff, Eric A; R"othlisberger, Daniela; Baker, David

New algorithms and an in silico benchmark for computational enzyme design Journal Article

In: Protein science : a publication of the Protein Society, vol. 15, pp. 2785-94, 2006, ISSN: 0961-8368.

Abstract | Links | BibTeX

73.

Ashworth, Justin; Havranek, James J; Duarte, Carlos M; Sussman, Django; Monnat, Raymond J; Stoddard, Barry L; Baker, David

Computational redesign of endonuclease DNA binding and cleavage specificity Journal Article

In: Nature, vol. 441, pp. 656-9, 2006, ISSN: 1476-4687.

Abstract | Links | BibTeX

74.

Lacy, D Borden; Lin, Henry C; Melnyk, Roman A; Schueler-Furman, Ora; Reither, Laura; Cunningham, Kristina; Baker, David; Collier, R John

A model of anthrax toxin lethal factor bound to protective antigen Journal Article

In: Proceedings of the National Academy of Sciences of the United States of America, vol. 102, pp. 16409-14, 2005, ISSN: 0027-8424.

Abstract | Links | BibTeX

75.

Korkegian, Aaron; Black, Margaret E; Baker, David; Stoddard, Barry L

Computational thermostabilization of an enzyme Journal Article

In: Science, vol. 308, pp. 857-60, 2005, ISSN: 1095-9203.

Abstract | Links | BibTeX

76.

Chevalier, Brett S; Kortemme, Tanja; Chadsey, Meggen S; Baker, David; Monnat, Raymond J; Stoddard, Barry L

Design, activity, and structure of a highly specific artificial endonuclease Journal Article

In: Molecular cell, vol. 10, pp. 895-905, 2002, ISSN: 1097-2765.

Abstract | Links | BibTeX

77.

Baker, D; Shiau, A K; Agard, D A

The role of pro regions in protein folding. Journal Article

In: Current Opinion in Cell Biology, vol. 5, pp. 966-70, 1993, ISSN: 0955-0674.

Abstract | Links | BibTeX

78.

Baker, D; Silen, J L; Agard, D A

Protease pro region required for folding is a potent inhibitor of the mature enzyme Journal Article

In: Proteins, vol. 12, pp. 339-44, 1992, ISSN: 0887-3585.

Abstract | BibTeX

78 entries « 4 of 4 »

 

2022

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2018

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2017–1998

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