cdbahl

Lab Information

First Name
Christopher
Last Name
Bahl
E-mail
cdbahl@uw.edu
Current Position
Senior Fellow
Room
MolE 420
webpage
http://scholar.google.com/citations?user=3-BbsnsAAAAJ

Personal blurb

Christopher D. Bahl

I am a post-doctoral fellow working on establishing a process for the de novo design of small, disulfide stabilized proteins. The goal is to create a method for developing idealized, super-stable protein scaffolds for use in engineering targeted protein binders.

Information about my previous work on the bacterial virulence factor Cif can be found here.

 

Publications

Bahl CD, Hvorecny KL, Bridges AA, Ballok AE, Bomberger JM, Cady KC, O'Toole GA, Madden DR (2014) Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity. J Biol Chem. 289, 7460-7469.

Amacher JF, Cushing PR, Bahl CD, Beck T, Madden DR (2013) Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-Binding Domains: A Novel Contribution of the Carboxylate-Binding Loop. J Biol Chem. 288, 5114-5126.

Ballok AE, Bahl CD, Dolben EL, Lindsay AK, St Laurent JD, Hogan DA, Madden DR, O'Toole GA (2012) Epoxide-mediated CifR repression of cif gene expression utilizes two binding sites in Pseudomonas aeruginosa. J Bacteriol. 194, 5315-5324.

Bahl CD, Madden DR (2012) Pseudomonas aeruginosa Cif defines a distinct class of α/β epoxide hydrolases utilizing a His/Tyr ring-opening pair. Protein Pept Lett. 19, 186-193.

Bahl CD, Morisseau C, Bomberger JM, Stanton BA, Hammock BD, O'Toole GA, Madden DR (2010) Crystal structure of the cystic fibrosis transmembrane conductance regulator inhibitory factor Cif reveals novel active-site features of an epoxide hydrolase virulence factor. J Bacteriol. 192, 1785-1795.

Bahl CD, MacEachran DP, O'Toole GA, Madden DR (2010) Purification, crystallization and preliminary X-ray diffraction analysis of Cif, a virulence factor secreted by Pseudomonas aeruginosa. Acta Crystallogr. F66, 26-28.


History

Member for
2 years 1 week