Ab initio protein structure prediction: progress and prospects.
|Title||Ab initio protein structure prediction: progress and prospects.|
|Publication Type||Journal Article|
|Year of Publication||2001|
|Authors||Bonneau, R., & Baker D.|
|Journal||Annual review of biophysics and biomolecular structure|
|Keywords||Algorithms, Genome, Models, Theoretical, Protein Conformation, Protein Folding, Protein Structure, Secondary, Protein Structure, Tertiary, Proteins, Software|
Considerable recent progress has been made in the field of ab initio protein structure prediction, as witnessed by the third Critical Assessment of Structure Prediction (CASP3). In spite of this progress, much work remains, for the field has yet to produce consistently reliable ab initio structure prediction protocols. In this work, we review the features of current ab initio protocols in an attempt to highlight the foundations of recent progress in the field and suggest promising directions for future work.
|Alternate Journal||Annu Rev Biophys Biomol Struct|