Ab initio protein structure prediction: progress and prospects.

TitleAb initio protein structure prediction: progress and prospects.
Publication TypeJournal Article
Year of Publication2001
AuthorsBonneau, R., & Baker D.
JournalAnnual review of biophysics and biomolecular structure
Volume30
Pagination173-89
Date Published2001
ISSN1056-8700
KeywordsAlgorithms, Genome, Models, Theoretical, Protein Conformation, Protein Folding, Protein Structure, Secondary, Protein Structure, Tertiary, Proteins, Software
Abstract

Considerable recent progress has been made in the field of ab initio protein structure prediction, as witnessed by the third Critical Assessment of Structure Prediction (CASP3). In spite of this progress, much work remains, for the field has yet to produce consistently reliable ab initio structure prediction protocols. In this work, we review the features of current ab initio protocols in an attempt to highlight the foundations of recent progress in the field and suggest promising directions for future work.

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http://www.ncbi.nlm.nih.gov/pubmed/11340057?dopt=Abstract

Alternate JournalAnnu Rev Biophys Biomol Struct