Protein structure prediction in 2002.

TitleProtein structure prediction in 2002.
Publication TypeJournal Article
Year of Publication2002
AuthorsSchonbrun, J., Wedemeyer W. J., & Baker D.
JournalCurrent opinion in structural biology
Volume12
Issue3
Pagination348-54
Date Published2002 Jun
ISSN0959-440X
KeywordsModels, Molecular, Protein Conformation, Protein Folding, Protein Structure, Tertiary, Sequence Analysis, Protein
Abstract

Central issues concerning protein structure prediction have been highlighted by the recently published summary of the fourth community-wide protein structure prediction experiment (CASP4). Although sequence/structure alignment remains the bottleneck in comparative modeling, there has been substantial progress in fully automated remote homolog detection and in de novo structure prediction. Significant further progress will probably require improvements in high-resolution modeling.

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http://www.ncbi.nlm.nih.gov/pubmed/12127454?dopt=Abstract

Alternate JournalCurr. Opin. Struct. Biol.