Protein structure prediction in 2002.
|Title||Protein structure prediction in 2002.|
|Publication Type||Journal Article|
|Year of Publication||2002|
|Authors||Schonbrun, J., Wedemeyer W. J., & Baker D.|
|Journal||Current opinion in structural biology|
|Date Published||2002 Jun|
|Keywords||Models, Molecular, Protein Conformation, Protein Folding, Protein Structure, Tertiary, Sequence Analysis, Protein|
Central issues concerning protein structure prediction have been highlighted by the recently published summary of the fourth community-wide protein structure prediction experiment (CASP4). Although sequence/structure alignment remains the bottleneck in comparative modeling, there has been substantial progress in fully automated remote homolog detection and in de novo structure prediction. Significant further progress will probably require improvements in high-resolution modeling.
|Alternate Journal||Curr. Opin. Struct. Biol.|