Free modeling with Rosetta in CASP6

TitleFree modeling with Rosetta in CASP6
Publication TypeJournal Article
Year of Publication2005
AuthorsBradley, P., Malmström L., Qian B., Schonbrun J., Chivian D., Kim D. E., Meiler J., Misura K. M. S., & Baker D.
Volume61 Suppl 7
Date Published2005
KeywordsAlgorithms, Computational Biology, Computer Simulation, Databases, Protein, Models, Molecular, Models, Theoretical, Primary Publication, Protein Conformation, Protein Folding, Protein Structure, Secondary, Protein Structure, Tertiary, Proteomics, Reproducibility of Results, Sequence Alignment, Software

We describe Rosetta predictions in the Sixth Community-Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP), focusing on the free modeling category. Methods developed since CASP5 are described, and their application to selected targets is discussed. Highlights include improved performance on larger proteins (100-200 residues) and the prediction of a 70-residue alpha-beta protein to near-atomic resolution.

Alternate JournalProteins
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